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NEOnatal Central-venous Line Observational study on Thrombosis (NEOCLOT): evaluation of a national guideline on management of neonatal catheter-related thrombosis

Overview of attention for article published in BMC Pediatrics, February 2018
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Title
NEOnatal Central-venous Line Observational study on Thrombosis (NEOCLOT): evaluation of a national guideline on management of neonatal catheter-related thrombosis
Published in
BMC Pediatrics, February 2018
DOI 10.1186/s12887-018-1000-7
Pubmed ID
Authors

Jeanine J. Sol, Moniek van de Loo, Marit Boerma, Klasien A. Bergman, Albertine E. Donker, Mark A. H. B. M. van der Hoeven, Christiaan V. Hulzebos, Ronny Knol, K. Djien Liem, Richard A. van Lingen, Enrico Lopriore, Monique H. Suijker, Daniel C. Vijlbrief, Remco Visser, Margreet A. Veening, Mirjam M. van Weissenbruch, C. Heleen van Ommen

Abstract

In critically ill (preterm) neonates, central venous catheters (CVCs) are increasingly used for administration of medication or parenteral nutrition. A serious complication, however, is the development of catheter-related thrombosis (CVC-thrombosis), which may resolve by itself or cause severe complications. Due to lack of evidence, management of neonatal CVC-thrombosis varies among neonatal intensive care units (NICUs). In the Netherlands an expert-based national management guideline has been developed which is implemented in all 10 NICUs in 2014. The NEOCLOT study is a multicentre prospective observational cohort study, including 150 preterm and term infants (0-6 months) admitted to one of the 10 NICUs, developing CVC-thrombosis. Patient characteristics, thrombosis characteristics, risk factors, treatment strategies and outcome measures will be collected in a web-based database. Management of CVC-thrombosis will be performed as recommended in the protocol. Violations of the protocol will be noted. Primary outcome measures are a composite efficacy outcome consisting of death due to CVC-thrombosis and recurrent thrombosis, and a safety outcome consisting of the incidence of major bleedings during therapy. Secondary outcomes include individual components of primary efficacy outcome, clinically relevant non-major and minor bleedings and the frequency of risk factors, protocol variations, residual thrombosis and post thrombotic syndrome. The NEOCLOT study will evaluate the efficacy and safety of the new, national, neonatal CVC-thrombosis guideline. Furthermore, risk factors as well as long-term consequences of CVC-thrombosis will be analysed. Trial registration: Nederlands Trial Register NTR4336 . Registered 24 December 2013.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Other 10 13%
Student > Postgraduate 9 12%
Student > Bachelor 7 9%
Researcher 7 9%
Student > Master 6 8%
Other 12 16%
Unknown 24 32%
Readers by discipline Count As %
Medicine and Dentistry 33 44%
Nursing and Health Professions 7 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Agricultural and Biological Sciences 1 1%
Veterinary Science and Veterinary Medicine 1 1%
Other 4 5%
Unknown 27 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2018.
All research outputs
#15,156,937
of 23,313,051 outputs
Outputs from BMC Pediatrics
#1,968
of 3,084 outputs
Outputs of similar age
#201,051
of 331,089 outputs
Outputs of similar age from BMC Pediatrics
#68
of 95 outputs
Altmetric has tracked 23,313,051 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,084 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,089 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.