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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The minimally effective dose of sucrose for procedural pain relief in neonates: a randomized controlled trial
|
|---|---|
| Published in |
BMC Pediatrics, February 2018
|
| DOI | 10.1186/s12887-018-1026-x |
| Pubmed ID | |
| Authors |
Bonnie Stevens, Janet Yamada, Marsha Campbell-Yeo, Sharyn Gibbins, Denise Harrison, Kimberley Dionne, Anna Taddio, Carol McNair, Andrew Willan, Marilyn Ballantyne, Kimberley Widger, Souraya Sidani, Carole Estabrooks, Anne Synnes, Janet Squires, Charles Victor, Shirine Riahi |
| Abstract |
Orally administered sucrose is effective and safe in reducing pain intensity during single, tissue-damaging procedures in neonates, and is commonly recommended in neonatal pain guidelines. However, there is wide variability in sucrose doses examined in research, and more than a 20-fold variation across neonatal care settings. The aim of this study was to determine the minimally effective dose of 24% sucrose for reducing pain in hospitalized neonates undergoing a single skin-breaking heel lance procedure. A total of 245 neonates from 4 Canadian tertiary neonatal intensive care units (NICUs), born between 24 and 42 weeks gestational age (GA), were prospectively randomized to receive one of three doses of 24% sucrose, plus non-nutritive sucking/pacifier, 2 min before a routine heel lance: 0.1 ml (Group 1; n = 81), 0.5 ml (Group 2; n = 81), or 1.0 ml (Group 3; n = 83). The primary outcome was pain intensity measured at 30 and 60 s following the heel lance, using the Premature Infant Pain Profile-Revised (PIPP-R). The secondary outcome was the incidence of adverse events. Analysis of covariance models, adjusting for GA and study site examined between group differences in pain intensity across intervention groups. There was no difference in mean pain intensity PIPP-R scores between treatment groups at 30 s (P = .97) and 60 s (P = .93); however, pain was not fully eliminated during the heel lance procedure. There were 5 reported adverse events among 5/245 (2.0%) neonates, with no significant differences in the proportion of events by sucrose dose (P = .62). All events resolved spontaneously without medical intervention. The minimally effective dose of 24% sucrose required to treat pain associated with a single heel lance in neonates was 0.1 ml. Further evaluation regarding the sustained effectiveness of this dose in reducing pain intensity in neonates for repeated painful procedures is warranted. ClinicalTrials.gov : NCT02134873. Date: May 5, 2014 (retrospectively registered). |
X Demographics
The data shown below were collected from the profiles of 36 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 14 | 39% |
| United States | 7 | 19% |
| Australia | 3 | 8% |
| United Kingdom | 2 | 6% |
| Ireland | 1 | 3% |
| Mexico | 1 | 3% |
| Unknown | 8 | 22% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 53% |
| Scientists | 11 | 31% |
| Practitioners (doctors, other healthcare professionals) | 6 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 208 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 27 | 13% |
| Student > Postgraduate | 12 | 6% |
| Student > Master | 12 | 6% |
| Student > Ph. D. Student | 10 | 5% |
| Researcher | 10 | 5% |
| Other | 42 | 20% |
| Unknown | 95 | 46% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 54 | 26% |
| Medicine and Dentistry | 31 | 15% |
| Unspecified | 3 | 1% |
| Agricultural and Biological Sciences | 3 | 1% |
| Engineering | 3 | 1% |
| Other | 14 | 7% |
| Unknown | 100 | 48% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2018.
All research outputs
#1,253,337
of 23,025,074 outputs
Outputs from BMC Pediatrics
#126
of 3,039 outputs
Outputs of similar age
#30,266
of 330,329 outputs
Outputs of similar age from BMC Pediatrics
#6
of 95 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,039 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,329 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.