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Molecular strategies to inhibit HIV-1 replication

Overview of attention for article published in Retrovirology, February 2005
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2 Wikipedia pages

Citations

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58 Dimensions

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114 Mendeley
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1 CiteULike
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Title
Molecular strategies to inhibit HIV-1 replication
Published in
Retrovirology, February 2005
DOI 10.1186/1742-4690-2-10
Pubmed ID
Authors

Morten Hjuler Nielsen, Finn Skou Pedersen, Jørgen Kjems

Abstract

The human immunodeficiency virus type 1 (HIV-1) is the primary cause of the acquired immunodeficiency syndrome (AIDS), which is a slow, progressive and degenerative disease of the human immune system. The pathogenesis of HIV-1 is complex and characterized by the interplay of both viral and host factors. An intense global research effort into understanding the individual steps of the viral replication cycle and the dynamics during an infection has inspired researchers in the development of a wide spectrum of antiviral strategies. Practically every stage in the viral life cycle and every viral gene product is a potential target. In addition, several strategies are targeting host proteins that play an essential role in the viral life cycle. This review summarizes the main genetic approaches taken in such antiviral strategies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 3 3%
United States 2 2%
Brazil 1 <1%
India 1 <1%
Italy 1 <1%
China 1 <1%
Denmark 1 <1%
Venezuela, Bolivarian Republic of 1 <1%
Puerto Rico 1 <1%
Other 0 0%
Unknown 102 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 18%
Student > Master 20 18%
Researcher 17 15%
Student > Bachelor 13 11%
Student > Postgraduate 7 6%
Other 17 15%
Unknown 19 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 42%
Biochemistry, Genetics and Molecular Biology 13 11%
Immunology and Microbiology 8 7%
Medicine and Dentistry 8 7%
Chemistry 5 4%
Other 14 12%
Unknown 18 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2010.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from Retrovirology
#455
of 1,273 outputs
Outputs of similar age
#25,501
of 72,954 outputs
Outputs of similar age from Retrovirology
#4
of 7 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 72,954 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.