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Temporary loss of moral behavior in a patient undergoing chemotherapy with cisplatin - breaking bad

Overview of attention for article published in BMC Psychiatry, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

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59 Mendeley
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Title
Temporary loss of moral behavior in a patient undergoing chemotherapy with cisplatin - breaking bad
Published in
BMC Psychiatry, February 2015
DOI 10.1186/s12888-015-0386-0
Pubmed ID
Authors

Kristian Barlinn, Hans Lehrach, Timo Siepmann, David Braeuer, Ulrich Buntrock, Norbert Sassim

Abstract

BackgroundBehavioral disturbances following chemotherapy with cisplatin are rare. Here, we report a patient with temporary loss of moral behavior in the setting of cisplatin-based chemotherapy for treatment of tonsillar cancer.Case presentationA 66-year-old Caucasian male with no psychiatric or violent history was started on chemotherapy with cisplatin for treatment of tonsillar cancer. During the following weeks, the patient developed profound personality changes involving volatile emotions and impulsive aggression with verbal and physical assaults on others. Admitted to the hospital, the patient lacked any awareness that his behavior was wrong. Chemotherapy was discontinued and the patient was prescribed risperidone. Aside from mild cognitive impairment, comprehensive neuropsychological, neuroradiological and lab testing were unremarkable. Three weeks following cessation of chemotherapy, the patient had recovered to his original mental state and he was completely aware of his wrongdoing and social misconduct.ConclusionSince neurotoxic effects of chemotherapeutics on the brain are not yet sufficiently elucidated, our case emphasizes that early signs of behavioral abnormalities in patients receiving chemotherapy should trigger comprehensive psychiatric evaluation and ongoing monitoring of the patients¿ mental state.

X Demographics

X Demographics

The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Unknown 58 98%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 8 14%
Student > Master 8 14%
Student > Ph. D. Student 7 12%
Student > Bachelor 7 12%
Researcher 5 8%
Other 12 20%
Unknown 12 20%
Readers by discipline Count As %
Psychology 12 20%
Nursing and Health Professions 9 15%
Medicine and Dentistry 7 12%
Pharmacology, Toxicology and Pharmaceutical Science 6 10%
Agricultural and Biological Sciences 5 8%
Other 8 14%
Unknown 12 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2015.
All research outputs
#1,498,830
of 24,978,429 outputs
Outputs from BMC Psychiatry
#483
of 5,314 outputs
Outputs of similar age
#20,911
of 363,438 outputs
Outputs of similar age from BMC Psychiatry
#11
of 74 outputs
Altmetric has tracked 24,978,429 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,314 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 363,438 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.