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Investigating the genetic role of aquaporin4 gene in migraine

Overview of attention for article published in The Journal of Headache and Pain, February 2009
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Title
Investigating the genetic role of aquaporin4 gene in migraine
Published in
The Journal of Headache and Pain, February 2009
DOI 10.1007/s10194-009-0100-z
Pubmed ID
Authors

Elisa Rubino, I. Rainero, G. Vaula, F. Crasto, E. Gravante, E. Negro, F. Brega, S. Gallone, L. Pinessi

Abstract

Aquaporin4 (AQP4) has an important role in water homeostasis of human brain and a dysfunction of AQP4 could induce pathological conditions in neuronal activity. The purpose of our work was to evaluate the association of polymorphisms in the AQP4 gene with the risk and the clinical features of migraine. A total of 293 migraineurs and 249 controls were involved in the study. They were genotyped for four single nucleotide polymorphisms (SNPs) of AQP4 gene. No significant difference in the distribution of AQP4 genotypic and allelic frequencies between cases and controls was found. In addition, haplotype analysis did not show any significant difference. Comparison of the clinical features of the disease according to different AQP4 genotypes showed no significant difference. Our data do not support the hypothesis that the AQP4 gene could represent a genetic susceptibility factor for migraine.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 22%
Other 2 11%
Professor 2 11%
Professor > Associate Professor 2 11%
Student > Master 2 11%
Other 5 28%
Unknown 1 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 22%
Biochemistry, Genetics and Molecular Biology 3 17%
Neuroscience 3 17%
Medicine and Dentistry 3 17%
Psychology 1 6%
Other 0 0%
Unknown 4 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2019.
All research outputs
#7,866,480
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#708
of 1,417 outputs
Outputs of similar age
#51,621
of 176,776 outputs
Outputs of similar age from The Journal of Headache and Pain
#3
of 6 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,776 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.