Title |
Escherichia coli from Crohn’s disease patient displays virulence features of enteroinvasive (EIEC), enterohemorragic (EHEC), and enteroaggregative (EAEC) pathotypes
|
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Published in |
Gut Pathogens, January 2015
|
DOI | 10.1186/s13099-015-0050-8 |
Pubmed ID | |
Authors |
Ana Carolina da Silva Santos, Fernando Gomes Romeiro, Ligia Yukie Sassaki, Josias Rodrigues |
Abstract |
Escherichia coli is a normal inhabitant of the gut which upon acquiring virulence factors becomes potentially able to cause diseases. Although E. coli population augments in Crohn's disease (CD), the reason of this proliferation is not yet clear. CD associated E. coli shows features of extraintestinal pathogenic categories (ExPEC), and eventually the ability to invade cultured epithelial cells, a property observed among diarrheagenic E. coli (DEC). In this work, data on the characterization of an E. coli isolate from a CD patient reveal that, besides invasiveness, CD associated E. coli may harbor other typical DEC markers, namely those defining enterohemorragic (EHEC) and enteroaggregative (EAEC) pathotypes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
New Zealand | 1 | 2% |
Argentina | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 51 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 16% |
Student > Bachelor | 9 | 16% |
Student > Ph. D. Student | 7 | 13% |
Student > Master | 7 | 13% |
Professor | 5 | 9% |
Other | 10 | 18% |
Unknown | 8 | 15% |
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Immunology and Microbiology | 7 | 13% |
Veterinary Science and Veterinary Medicine | 2 | 4% |
Medicine and Dentistry | 2 | 4% |
Other | 4 | 7% |
Unknown | 12 | 22% |