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Selection of functional mutations in the U5-IR stem and loop regions of the Rous sarcoma virus genome

Overview of attention for article published in BMC Biology, May 2004
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Title
Selection of functional mutations in the U5-IR stem and loop regions of the Rous sarcoma virus genome
Published in
BMC Biology, May 2004
DOI 10.1186/1741-7007-2-8
Pubmed ID
Authors

Michael Johnson, Shannon Morris, Aiping Chen, Ed Stavnezer, Jonathan Leis

Abstract

The 5' end of the Rous sarcoma virus (RSV) RNA around the primer-binding site forms a series of RNA secondary stem/loop structures (U5-IR stem, TpsiC interaction region, U5-leader stem) that are required for efficient initiation of reverse transcription. The U5-IR stem and loop also encode the U5 integrase (IN) recognition sequence at the level of DNA such that this region has overlapping biological functions in reverse transcription and integration.

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Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Researcher 2 22%
Student > Master 2 22%
Unknown 2 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 1 11%
Social Sciences 1 11%
Medicine and Dentistry 1 11%
Engineering 1 11%
Other 0 0%
Unknown 3 33%