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A low-protein diet during pregnancy prevents modifications in intercellular communication proteins in rat islets

Overview of attention for article published in Biological Research, January 2015
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Title
A low-protein diet during pregnancy prevents modifications in intercellular communication proteins in rat islets
Published in
Biological Research, January 2015
DOI 10.1186/0717-6287-48-3
Pubmed ID
Authors

Ana Flávia Marçal-Pessoa, Carmen Lucia Bassi-Branco, Cristiana dos Santos Barbosa Salvatierra, Luiz Fabrizio Stoppiglia, Letícia Martins Ignacio-Souza, Sílvia Regina de Lima Reis, Roberto Vilela Veloso, Marise Auxiliadora de Barros Reis, Everardo Magalhães Carneiro, Antonio Carlos Boschero, Vanessa Cristina Arantes, Márcia Queiroz Latorraca

Abstract

Gap junctions between β-cells participate in the precise regulation of insulin secretion. Adherens junctions and their associated proteins are required for the formation, function and structural maintenance of gap junctions. Increases in the number of the gap junctions between β-cells and enhanced glucose-stimulated insulin secretion are observed during pregnancy. In contrast, protein restriction produces structural and functional alterations that result in poor insulin secretion in response to glucose. We investigated whether protein restriction during pregnancy affects the expression of mRNA and proteins involved in gap and adherens junctions in pancreatic islets. An isoenergetic low-protein diet (6% protein) was fed to non-pregnant or pregnant rats from day 1-15 of pregnancy, and rats fed an isocaloric normal-protein diet (17% protein) were used as controls.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 17%
Student > Bachelor 3 13%
Student > Postgraduate 3 13%
Student > Master 3 13%
Student > Doctoral Student 2 9%
Other 2 9%
Unknown 6 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 17%
Nursing and Health Professions 3 13%
Agricultural and Biological Sciences 3 13%
Engineering 2 9%
Medicine and Dentistry 2 9%
Other 2 9%
Unknown 7 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2015.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Biological Research
#601
of 642 outputs
Outputs of similar age
#307,792
of 360,070 outputs
Outputs of similar age from Biological Research
#11
of 14 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 642 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,070 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.