Title |
Tissue interactions in the developing chick diencephalon
|
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Published in |
Neural Development, November 2007
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DOI | 10.1186/1749-8104-2-25 |
Pubmed ID | |
Authors |
Maria Flavia Guinazu, David Chambers, Andrew Lumsden, Clemens Kiecker |
Abstract |
The developing vertebrate brain is patterned first by global signalling gradients that define crude anteroposterior and dorsoventral coordinates, and subsequently by local signalling centres (organisers) that refine cell fate assignment within pre-patterned regions. The interface between the prethalamus and the thalamus, the zona limitans intrathalamica (ZLI), is one such local signalling centre that is essential for the establishment of these major diencephalic subdivisions by secreting the signalling factor Sonic hedgehog. Various models for ZLI formation have been proposed, but a thorough understanding of how this important local organiser is established is lacking. |
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Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 24% |
Student > Master | 6 | 16% |
Student > Bachelor | 4 | 11% |
Student > Ph. D. Student | 4 | 11% |
Student > Doctoral Student | 3 | 8% |
Other | 8 | 21% |
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Readers by discipline | Count | As % |
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Unspecified | 1 | 3% |
Other | 4 | 11% |
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