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Improved methods for magnetic purification of malaria parasites and haemozoin

Overview of attention for article published in Malaria Journal, January 2010
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Mentioned by

twitter
1 X user
wikipedia
5 Wikipedia pages

Citations

dimensions_citation
36 Dimensions

Readers on

mendeley
109 Mendeley
citeulike
1 CiteULike
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Title
Improved methods for magnetic purification of malaria parasites and haemozoin
Published in
Malaria Journal, January 2010
DOI 10.1186/1475-2875-9-17
Pubmed ID
Authors

Charles C Kim, Emily B Wilson, Joseph L DeRisi

Abstract

Malaria parasites generate free haem upon catabolism of host haemoglobin during their intraerythrocytic growth cycle. In order to minimize oxidative toxicity of the ferric iron, the free haem molecules are polymerized into the biomineral beta-haematin (commonly referred to as haemozoin). Haemozoin crystals are paramagnetic, and this property can be exploited for the purification of late stage parasites as they contain larger haemozoin crystals than early stage parasites and uninfected cells. Commercially available magnets that were originally developed for the purpose of antibody-mediated cell purification are widely used for this purpose. As these methods are not necessarily optimized for parasite purification, the relationship between magnetic field strength and the quantity and quality of yield during parasite purification was explored.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Canada 2 2%
United Kingdom 1 <1%
Brazil 1 <1%
Unknown 102 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 30%
Student > Bachelor 14 13%
Researcher 13 12%
Student > Master 12 11%
Student > Doctoral Student 7 6%
Other 16 15%
Unknown 14 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 37%
Biochemistry, Genetics and Molecular Biology 16 15%
Engineering 13 12%
Physics and Astronomy 8 7%
Immunology and Microbiology 7 6%
Other 9 8%
Unknown 16 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2021.
All research outputs
#6,413,521
of 22,786,691 outputs
Outputs from Malaria Journal
#1,852
of 5,560 outputs
Outputs of similar age
#41,360
of 164,953 outputs
Outputs of similar age from Malaria Journal
#16
of 38 outputs
Altmetric has tracked 22,786,691 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 5,560 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,953 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.