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Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis

Overview of attention for article published in Microbial Cell Factories, January 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
3 X users
patent
2 patents
wikipedia
6 Wikipedia pages

Citations

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189 Dimensions

Readers on

mendeley
148 Mendeley
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Title
Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis
Published in
Microbial Cell Factories, January 2007
DOI 10.1186/1475-2859-6-1
Pubmed ID
Authors

Luciana S Cardoso, Maria Ilma Araujo, Alfredo M Góes, Lucila G Pacífico, Ricardo R Oliveira, Sergio C Oliveira

Abstract

Recombinant proteins expressed in Escherichia coli vectors are generally contaminated with endotoxin. In this study, we evaluated the ability of Polymyxin B to neutralize the effect of LPS present as contaminant on Schistosoma mansoni recombinant proteins produced in E. coli in inducing TNF-alpha and IL-10. Peripheral blood mononuclear cells from individuals chronically infected with S. mansoni were stimulated in vitro with recombinant Sm22.6, Sm14 and P24 antigens (10 microg/mL) in the presence of Polymyxin B (10 microg/mL).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 3%
Spain 1 <1%
Portugal 1 <1%
Brazil 1 <1%
Unknown 140 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 28%
Student > Bachelor 22 15%
Researcher 21 14%
Student > Master 16 11%
Student > Doctoral Student 12 8%
Other 15 10%
Unknown 21 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 41%
Immunology and Microbiology 20 14%
Biochemistry, Genetics and Molecular Biology 16 11%
Medicine and Dentistry 15 10%
Computer Science 2 1%
Other 10 7%
Unknown 24 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2024.
All research outputs
#3,061,514
of 25,373,627 outputs
Outputs from Microbial Cell Factories
#108
of 1,823 outputs
Outputs of similar age
#11,182
of 168,752 outputs
Outputs of similar age from Microbial Cell Factories
#1
of 5 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,823 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,752 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them