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Risk for rheumatic disease in relation to ethnicity and admixture

Overview of attention for article published in Arthritis Research & Therapy, February 2000
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70 Mendeley
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Title
Risk for rheumatic disease in relation to ethnicity and admixture
Published in
Arthritis Research & Therapy, February 2000
DOI 10.1186/ar76
Pubmed ID
Authors

Mariam Molokhia, Paul McKeigue

Abstract

Risk of systemic lupus erythematosus (SLE) is high in west Africans compared with Europeans, and risk of rheumatoid arthritis (RA) is high in Native Americans compared with Europeans. These differences are not accounted for by differences in allele or haplotype frequencies in the human leucocyte antigen (HLA) region or any other loci known to influence risk of rheumatic disease. Where there has been admixture between two or more ethnic groups that differ in risk of disease, studies of the relationship of disease risk to proportionate admixture can help to distinguish between genetic and environmental explanations for ethnic differences in disease risk and to map the genes underlying these differences.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 1%
Switzerland 1 1%
Unknown 68 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 16%
Student > Master 10 14%
Researcher 9 13%
Student > Bachelor 6 9%
Professor > Associate Professor 5 7%
Other 19 27%
Unknown 10 14%
Readers by discipline Count As %
Medicine and Dentistry 26 37%
Agricultural and Biological Sciences 12 17%
Biochemistry, Genetics and Molecular Biology 7 10%
Psychology 2 3%
Neuroscience 2 3%
Other 6 9%
Unknown 15 21%