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Overview of attention for article published in Genome Biology (Online Edition), January 2004
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)

Mentioned by

1 patent
5 Wikipedia pages


171 Dimensions

Readers on

310 Mendeley
2 CiteULike
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Published in
Genome Biology (Online Edition), January 2004
DOI 10.1186/gb-2004-5-7-234
Pubmed ID

Hui-Chuan Huang, Peter S Klein


Frizzled genes encode integral membrane proteins that function in multiple signal transduction pathways. They have been identified in diverse animals, from sponges to humans. The family is defined by conserved structural features, including seven hydrophobic domains and a cysteine-rich ligand-binding domain. Frizzled proteins are receptors for secreted Wnt proteins, as well as other ligands, and also play a critical role in the regulation of cell polarity. Frizzled genes are essential for embryonic development, tissue and cell polarity, formation of neural synapses, and the regulation of proliferation, and many other processes in developing and adult organisms; mutations in human frizzled-4 have been linked to familial exudative vitreoretinopathy. It is not yet clear how Frizzleds couple to downstream effectors, and this is a focus of intense study.

Mendeley readers

The data shown below were compiled from readership statistics for 310 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
France 2 <1%
Portugal 1 <1%
Germany 1 <1%
Norway 1 <1%
Italy 1 <1%
Chile 1 <1%
Brazil 1 <1%
Austria 1 <1%
Other 2 <1%
Unknown 297 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 93 30%
Student > Bachelor 52 17%
Researcher 39 13%
Student > Master 32 10%
Professor > Associate Professor 12 4%
Other 40 13%
Unknown 42 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 111 36%
Biochemistry, Genetics and Molecular Biology 90 29%
Medicine and Dentistry 13 4%
Chemistry 12 4%
Neuroscience 9 3%
Other 31 10%
Unknown 44 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2022.
All research outputs
of 20,975,194 outputs
Outputs from Genome Biology (Online Edition)
of 3,995 outputs
Outputs of similar age
of 319,992 outputs
Outputs of similar age from Genome Biology (Online Edition)
of 6 outputs
Altmetric has tracked 20,975,194 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,995 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,992 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.