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Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection

Overview of attention for article published in Retrovirology, March 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#48 of 1,151)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
1 news outlet
blogs
2 blogs
twitter
8 X users
wikipedia
5 Wikipedia pages

Citations

dimensions_citation
75 Dimensions

Readers on

mendeley
83 Mendeley
connotea
1 Connotea
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Title
Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection
Published in
Retrovirology, March 2011
DOI 10.1186/1742-4690-8-16
Pubmed ID
Authors

Suzanne Willey, Marlén MI Aasa-Chapman, Stephen O'Farrell, Pierre Pellegrino, Ian Williams, Robin A Weiss, Stuart JD Neil

Abstract

Non-neutralising antibodies to the envelope glycoprotein are elicited during acute HIV-1 infection and are abundant throughout the course of disease progression. Although these antibodies appear to have negligible effects on HIV-1 infection when assayed in standard neutralisation assays, they have the potential to exert either inhibitory or enhancing effects through interactions with complement and/or Fc receptors. Here we report that non-neutralising antibodies produced early in response to HIV-1 infection can enhance viral infectivity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Belgium 1 1%
Unknown 81 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 23%
Student > Ph. D. Student 13 16%
Student > Master 10 12%
Student > Bachelor 8 10%
Other 6 7%
Other 14 17%
Unknown 13 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 29%
Immunology and Microbiology 16 19%
Biochemistry, Genetics and Molecular Biology 12 14%
Medicine and Dentistry 10 12%
Engineering 2 2%
Other 7 8%
Unknown 12 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2023.
All research outputs
#1,425,573
of 25,321,938 outputs
Outputs from Retrovirology
#48
of 1,151 outputs
Outputs of similar age
#5,315
of 114,532 outputs
Outputs of similar age from Retrovirology
#1
of 7 outputs
Altmetric has tracked 25,321,938 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 114,532 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them