Title |
Low-pass sequencing for microbial comparative genomics
|
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Published in |
BMC Genomics, January 2004
|
DOI | 10.1186/1471-2164-5-3 |
Pubmed ID | |
Authors |
Young Ah Goo, Jared Roach, Gustavo Glusman, Nitin S Baliga, Kerry Deutsch, Min Pan, Sean Kennedy, Shiladitya DasSarma, Wailap Victor Ng, Leroy Hood |
Abstract |
We studied four extremely halophilic archaea by low-pass shotgun sequencing: (1) the metabolically versatile Haloarcula marismortui; (2) the non-pigmented Natrialba asiatica; (3) the psychrophile Halorubrum lacusprofundi and (4) the Dead Sea isolate Halobaculum gomorrense. Approximately one thousand single pass genomic sequences per genome were obtained. The data were analyzed by comparative genomic analyses using the completed Halobacterium sp. NRC-1 genome as a reference. Low-pass shotgun sequencing is a simple, inexpensive, and rapid approach that can readily be performed on any cultured microbe. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 9% |
Brazil | 2 | 4% |
United Kingdom | 1 | 2% |
Unknown | 46 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 24% |
Student > Ph. D. Student | 9 | 17% |
Student > Master | 8 | 15% |
Professor > Associate Professor | 5 | 9% |
Other | 4 | 7% |
Other | 8 | 15% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 30 | 56% |
Biochemistry, Genetics and Molecular Biology | 9 | 17% |
Engineering | 3 | 6% |
Environmental Science | 2 | 4% |
Unspecified | 1 | 2% |
Other | 2 | 4% |
Unknown | 7 | 13% |