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Pertussis outbreak in university students and evaluation of acellular pertussis vaccine effectiveness in Japan

Overview of attention for article published in BMC Infectious Diseases, February 2015
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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2 Facebook pages

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Title
Pertussis outbreak in university students and evaluation of acellular pertussis vaccine effectiveness in Japan
Published in
BMC Infectious Diseases, February 2015
DOI 10.1186/s12879-015-0777-3
Pubmed ID
Authors

Megumi Hara, Mami Fukuoka, Katsuya Tashiro, Iwata Ozaki, Satoko Ohfuji, Kenji Okada, Takashi Nakano, Wakaba Fukushima, Yoshio Hirota

Abstract

BackgroundRecent studies worldwide have reported increasing numbers of adults diagnosed with Bordetella pertussis despite receiving childhood vaccinations. This study describes a pertussis outbreak at a university medical faculty campus and examines the effectiveness of diphtheria, tetanus, and pertussis (DTaP) vaccination completed during infancy in Japan.MethodsAfter the outbreak, self-administered questionnaires and serum samples were collected from students on campus to determine the incidence of pertussis and underlying diseases. Pertussis was diagnosed on the basis of clinical criteria and serum anti-pertussis toxin antibody levels. Using data collected from 248 first and second grade students who had submitted copies of their vaccination records, we evaluated the effectiveness of DTaP vaccination in infancy against adult pertussis.ResultsQuestionnaire responses were obtained from 636 students (of 671 registered students; 95% response rate). Of 245 students who reported a continuous cough during the outbreak period, 84 (attack rate: 13.2%) were considered ¿probable¿ pertussis cases that met clinical criteria. The outbreak occurred mainly in first and second grade students in the Faculty of Medicine. Of 248 students who provided vaccination records, 225 had received 4 DTaP doses (coverage: 90.7%); the relative risk of the complete vaccination series compared to those with fewer than 4 doses or no doses for probable cases was 0.48 (95% confidence interval: 0.24-0.97).ConclusionsWaning protection was suspected due to over time. Booster vaccination for teenagers and development of highly efficacious pertussis vaccines are needed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Canada 1 2%
Unknown 46 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 27%
Student > Ph. D. Student 6 13%
Student > Bachelor 6 13%
Other 3 6%
Professor > Associate Professor 2 4%
Other 6 13%
Unknown 12 25%
Readers by discipline Count As %
Medicine and Dentistry 16 33%
Biochemistry, Genetics and Molecular Biology 4 8%
Agricultural and Biological Sciences 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Nursing and Health Professions 1 2%
Other 4 8%
Unknown 16 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2015.
All research outputs
#13,920,963
of 23,848,132 outputs
Outputs from BMC Infectious Diseases
#3,366
of 7,988 outputs
Outputs of similar age
#175,744
of 357,971 outputs
Outputs of similar age from BMC Infectious Diseases
#58
of 151 outputs
Altmetric has tracked 23,848,132 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,988 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 357,971 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 151 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.