Title |
CD133 antigen expression in ovarian cancer
|
---|---|
Published in |
BMC Cancer, July 2009
|
DOI | 10.1186/1471-2407-9-221 |
Pubmed ID | |
Authors |
Gabriella Ferrandina, Enrica Martinelli, Marco Petrillo, Maria Grazia Prisco, Gianfranco Zannoni, Stefano Sioletic, Giovanni Scambia |
Abstract |
Much attention has been recently focused on the role of cancer stem cells (CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to proliferate and self-renew extensively, thus sustaining tumor growth, the identification of CSCs through their antigenic profile might have relevant clinical implications. In this context, CD133 antigen has proved to be a marker of tumor cells with stemness features in several human malignancies.The aim of the study was to investigate the clinical role of the immunohistochemically assessed expression of CD133 in a large single Institution series of ovarian cancer patients. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Hungary | 1 | 2% |
Australia | 1 | 2% |
Unknown | 39 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 17% |
Researcher | 7 | 17% |
Student > Ph. D. Student | 7 | 17% |
Student > Doctoral Student | 6 | 14% |
Student > Bachelor | 5 | 12% |
Other | 5 | 12% |
Unknown | 5 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 38% |
Agricultural and Biological Sciences | 11 | 26% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Veterinary Science and Veterinary Medicine | 2 | 5% |
Mathematics | 1 | 2% |
Other | 4 | 10% |
Unknown | 3 | 7% |