Title |
Cloning, characterization and expression analysis of porcine microRNAs
|
---|---|
Published in |
BMC Genomics, February 2009
|
DOI | 10.1186/1471-2164-10-65 |
Pubmed ID | |
Authors |
Alavala Matta Reddy, Yun Zheng, Guru Jagadeeswaran, Simone L Macmil, Wiley B Graham, Bruce A Roe, Udaya Desilva, Weixiong Zhang, Ramanjulu Sunkar |
Abstract |
MicroRNAs (miRNAs) are small ~22-nt regulatory RNAs that can silence target genes, by blocking their protein production or degrading the mRNAs. Pig is an important animal in the agriculture industry because of its utility in the meat production. Besides, pig has tremendous biomedical importance as a model organism because of its closer proximity to humans than the mouse model. Several hundreds of miRNAs have been identified from mammals, humans, mice and rats, but little is known about the miRNA component in the pig genome. Here, we adopted an experimental approach to identify conserved and unique miRNAs and characterize their expression patterns in diverse tissues of pig. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
India | 1 | 1% |
Denmark | 1 | 1% |
Italy | 1 | 1% |
Unknown | 88 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 18% |
Researcher | 16 | 17% |
Student > Master | 12 | 13% |
Professor | 9 | 10% |
Other | 7 | 8% |
Other | 19 | 20% |
Unknown | 13 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 45 | 48% |
Biochemistry, Genetics and Molecular Biology | 13 | 14% |
Medicine and Dentistry | 11 | 12% |
Computer Science | 3 | 3% |
Engineering | 2 | 2% |
Other | 6 | 6% |
Unknown | 13 | 14% |