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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The protocol of the Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial
|
|---|---|
| Published in |
BMC Geriatrics, February 2015
|
| DOI | 10.1186/s12877-015-0006-3 |
| Pubmed ID | |
| Authors |
Bjørn Erik Neerland, Karen Roksund Hov, Vegard Bruun Wyller, Eirik Qvigstad, Eva Skovlund, Alasdair MJ MacLullich, Torgeir Bruun Wyller |
| Abstract |
Delirium affects 15% of hospitalised patients and is linked with poor outcomes, yet few pharmacological treatment options exist. One hypothesis is that delirium may in part result from exaggerated and/or prolonged stress responses. Dexmedetomidine, a parenterally-administered alpha2-adrenergic receptor agonist which attenuates sympathetic nervous system activity, shows promise as treatment in ICU delirium. Clonidine exhibits similar pharmacodynamic properties and can be administered orally. We therefore wish to explore possible effects of clonidine upon the duration and severity of delirium in general medical inpatients. The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is a randomised, placebo-controlled, double-blinded, parallel group study with 4-month prospective follow-up. We will recruit 100 older medical inpatients with delirium or subsyndromal delirium in the acute geriatric ward. Participants will be randomised to oral clonidine or placebo until delirium free for 2 days (Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria), or after a maximum of 7 days treatment. Assessment of haemodynamics (blood pressure, heart rate and electrocardiogram) and delirium will be performed daily until discharge or a maximum of 7 days after end of treatment. The primary endpoint is the trajectory of delirium over time (measured by Memorial Delirium Assessment Scale). Secondary endpoints include the duration of delirium, use of rescue medication for delirium, pharmacokinetics and pharmacodynamics of clonidine, cognitive function after 4 months, length of hospital stay and need for institutionalisation. LUCID will explore the efficacy and safety of clonidine for delirium in older medical inpatients. ClinicalTrials.gov NCT01956604 . EudraCT Number: 2013-000815-26. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 7 | 28% |
| United States | 6 | 24% |
| Netherlands | 2 | 8% |
| Germany | 1 | 4% |
| Ireland | 1 | 4% |
| Australia | 1 | 4% |
| Norway | 1 | 4% |
| Unknown | 6 | 24% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 48% |
| Scientists | 7 | 28% |
| Practitioners (doctors, other healthcare professionals) | 5 | 20% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Unknown | 112 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 17% |
| Student > Bachelor | 13 | 12% |
| Researcher | 12 | 11% |
| Student > Ph. D. Student | 10 | 9% |
| Student > Postgraduate | 8 | 7% |
| Other | 25 | 22% |
| Unknown | 26 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 38% |
| Nursing and Health Professions | 9 | 8% |
| Psychology | 7 | 6% |
| Neuroscience | 5 | 4% |
| Computer Science | 4 | 4% |
| Other | 18 | 16% |
| Unknown | 27 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2019.
All research outputs
#2,749,866
of 25,402,889 outputs
Outputs from BMC Geriatrics
#713
of 3,649 outputs
Outputs of similar age
#38,667
of 366,809 outputs
Outputs of similar age from BMC Geriatrics
#6
of 27 outputs
Altmetric has tracked 25,402,889 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,649 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 366,809 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.