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Relating tissue specialization to the differentiation of expression of singleton and duplicate mouse proteins

Overview of attention for article published in Genome Biology, October 2006
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Title
Relating tissue specialization to the differentiation of expression of singleton and duplicate mouse proteins
Published in
Genome Biology, October 2006
DOI 10.1186/gb-2006-7-10-r89
Pubmed ID
Authors

Shiri Freilich, Tim Massingham, Eric Blanc, Leon Goldovsky, Janet M Thornton

Abstract

Gene duplications have been hypothesized to be a major factor in enabling the evolution of tissue differentiation. Analyses of the expression profiles of duplicate genes in mammalian tissues have indicated that, with time, the expression patterns of duplicate genes diverge and become more tissue specific. We explored the relationship between duplication events, the time at which they took place, and both the expression breadth of the duplicated genes and the cumulative expression breadth of the gene family to which they belong.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
France 1 3%
Germany 1 3%
Belgium 1 3%
Unknown 25 86%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 28%
Student > Ph. D. Student 6 21%
Professor > Associate Professor 4 14%
Other 2 7%
Student > Doctoral Student 2 7%
Other 5 17%
Unknown 2 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 66%
Biochemistry, Genetics and Molecular Biology 4 14%
Business, Management and Accounting 2 7%
Earth and Planetary Sciences 1 3%
Medicine and Dentistry 1 3%
Other 0 0%
Unknown 2 7%