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Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000

Overview of attention for article published in BMC Pharmacology, December 2008
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3 Wikipedia pages

Citations

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38 Dimensions

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28 Mendeley
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Title
Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000
Published in
BMC Pharmacology, December 2008
DOI 10.1186/1471-2210-8-20
Pubmed ID
Authors

Zhan-Guo Gao, Kai Ye, Anikó Göblyös, Adriaan P IJzerman, Kenneth A Jacobson

Abstract

A series of 1H-imidazo- [4,5-c]quinolin-4-amine derivatives, represented by LUF6000 (N-(3,4-dichloro-phenyl)-2-cyclohexyl-1H-imidazo [4,5-c]quinolin-4-amine), are allosteric modulators of the human A3 adenosine receptor (AR). Here we studied the modulation by LUF6000 of the maximum effect (Emax) of structurally diverse agonists at the A3 AR stably expressed in CHO cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Netherlands 1 4%
Belgium 1 4%
Unknown 25 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 32%
Student > Ph. D. Student 5 18%
Student > Master 3 11%
Student > Bachelor 2 7%
Student > Postgraduate 2 7%
Other 5 18%
Unknown 2 7%
Readers by discipline Count As %
Chemistry 11 39%
Agricultural and Biological Sciences 4 14%
Biochemistry, Genetics and Molecular Biology 3 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Medicine and Dentistry 2 7%
Other 3 11%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2021.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from BMC Pharmacology
#26
of 63 outputs
Outputs of similar age
#47,555
of 165,183 outputs
Outputs of similar age from BMC Pharmacology
#2
of 2 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 63 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,183 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.