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Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts

Overview of attention for article published in Molecular Cancer, August 2013
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

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3 Wikipedia pages

Citations

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47 Dimensions

Readers on

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63 Mendeley
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Title
Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts
Published in
Molecular Cancer, August 2013
DOI 10.1186/1476-4598-12-89
Pubmed ID
Authors

Enas A El-Karim, Engda G Hagos, Amr M Ghaleb, Bing Yu, Vincent W Yang

Abstract

Krüppel-like factor 4 (KLF4) is a member of the KLF family of transcription factors and regulates proliferation, differentiation, apoptosis and somatic cell reprogramming. Evidence also suggests that KLF4 is a tumor suppressor in certain cancers including colorectal cancer. We previously showed that KLF4 inhibits cell cycle progression following DNA damage and that mouse embryonic fibroblasts (MEFs) null for Klf4 are genetically unstable, as evidenced by increased rates of cell proliferation, and the presence of DNA double strand breaks (DSBs), centrosome amplification, chromosome aberrations and aneuploidy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 25%
Student > Ph. D. Student 10 16%
Student > Master 10 16%
Researcher 6 10%
Student > Doctoral Student 2 3%
Other 9 14%
Unknown 10 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 40%
Agricultural and Biological Sciences 17 27%
Medicine and Dentistry 4 6%
Immunology and Microbiology 2 3%
Nursing and Health Professions 1 2%
Other 3 5%
Unknown 11 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2022.
All research outputs
#7,754,533
of 23,571,271 outputs
Outputs from Molecular Cancer
#578
of 1,779 outputs
Outputs of similar age
#66,673
of 198,716 outputs
Outputs of similar age from Molecular Cancer
#3
of 9 outputs
Altmetric has tracked 23,571,271 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,779 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,716 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.