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Mutational analyses of the signals involved in the subcellular location of DSCR1

Overview of attention for article published in BMC Molecular and Cell Biology, September 2002
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Title
Mutational analyses of the signals involved in the subcellular location of DSCR1
Published in
BMC Molecular and Cell Biology, September 2002
DOI 10.1186/1471-2121-3-24
Pubmed ID
Authors

Sandra Cristina Pfister, Gláucia Maria Machado-Santelli, Sang Won Han, Flávio Henrique-Silva

Abstract

Down syndrome is the most frequent genetic disorder in humans. Rare cases involving partial trisomy of chromosome 21 allowed a small chromosomal region common to all carriers, called Down Syndrome Critical Region (DSCR), to be determined. The DSCR1 gene was identified in this region and is expressed preferentially in the brain, heart and skeletal muscle. Recent studies have shown that DSCR1 belongs to a family of proteins that binds and inhibits calcineurin, a serine-threonine phosphatase. The work reported on herein consisted of a study of the subcellular location of DSCR1 and DSCR1-mutated forms by fusion with a green fluorescent protein, using various cell lines, including human.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 25%
Other 2 13%
Student > Doctoral Student 2 13%
Student > Postgraduate 2 13%
Student > Master 2 13%
Other 3 19%
Unknown 1 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 44%
Biochemistry, Genetics and Molecular Biology 4 25%
Medicine and Dentistry 1 6%
Neuroscience 1 6%
Engineering 1 6%
Other 0 0%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2009.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#334
of 1,233 outputs
Outputs of similar age
#17,077
of 49,152 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#4
of 5 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 49,152 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.