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Low-resolution structural studies of human Stanniocalcin-1

Overview of attention for article published in BMC Molecular and Cell Biology, August 2009
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Title
Low-resolution structural studies of human Stanniocalcin-1
Published in
BMC Molecular and Cell Biology, August 2009
DOI 10.1186/1472-6807-9-57
Pubmed ID
Authors

Daniel M Trindade, Júlio C Silva, Margareth S Navarro, Iris CL Torriani, Jörg Kobarg

Abstract

Stanniocalcins (STCs) represent small glycoprotein hormones, found in all vertebrates, which have been functionally implicated in Calcium homeostasis. However, recent data from mammalian systems indicated that they may be also involved in embryogenesis, tumorigenesis and in the context of the latter especially in angiogenesis. Human STC1 is a 247 amino acids protein with a predicted molecular mass of 27 kDa, but preliminary data suggested its di- or multimerization. The latter in conjunction with alternative splicing and/or post-translational modification gives rise to forms described as STC50 and "big STC", which molecular weights range from 56 to 135 kDa.

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Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 22%
Researcher 6 22%
Student > Master 4 15%
Student > Ph. D. Student 4 15%
Professor > Associate Professor 2 7%
Other 4 15%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 37%
Biochemistry, Genetics and Molecular Biology 6 22%
Chemistry 2 7%
Arts and Humanities 1 4%
Business, Management and Accounting 1 4%
Other 3 11%
Unknown 4 15%