Title |
The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
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Published in |
BMC Molecular and Cell Biology, January 2005
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DOI | 10.1186/1471-2121-6-1 |
Pubmed ID | |
Authors |
Marleen MR Petit, Sandra MP Meulemans, Philippe Alen, Torik AY Ayoubi, Erik Jansen, Wim JM Van de Ven |
Abstract |
At sites of cell adhesion, proteins exist that not only perform structural tasks but also have a signaling function. Previously, we found that the Lipoma Preferred Partner (LPP) protein is localized at sites of cell adhesion such as focal adhesions and cell-cell contacts, and shuttles to the nucleus where it has transcriptional activation capacity. LPP is a member of the zyxin family of proteins, which contains five members: ajuba, LIMD1, LPP, TRIP6 and zyxin. LPP has three LIM domains (zinc-finger protein interaction domains) at its carboxy-terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
United States | 1 | 2% |
Unknown | 50 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 19% |
Researcher | 9 | 17% |
Student > Master | 7 | 13% |
Student > Bachelor | 6 | 12% |
Student > Postgraduate | 4 | 8% |
Other | 7 | 13% |
Unknown | 9 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 50% |
Biochemistry, Genetics and Molecular Biology | 11 | 21% |
Computer Science | 2 | 4% |
Medicine and Dentistry | 2 | 4% |
Immunology and Microbiology | 1 | 2% |
Other | 2 | 4% |
Unknown | 8 | 15% |