Sample size implications of mortality definitions in sepsis: a retrospective cohort study

Research in #Trialsjorunal highlights event rates vary substantially in sepsis patients based on the chosen 90-day mortality definition; imp. implications for RCT design trade-offs: https://t.co/gkZiRF60sF

Mortality definitions- is this issue really about power? I would have thought the preference for RCT would be all location mortality (if feasible). Different definitions will alter the RQ - so select based on RQ rather than efficiency. Or am I being too i

RT @MedicalEvidence: Sample size implications of mortality definitions in sepsis - a retrospective cohort study via #Trialsjournal: https:/…

Sample size implications of mortality definitions in sepsis - a retrospective cohort study via #Trialsjournal: https://t.co/gkZiRFnBRf