↓ Skip to main content

Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain

Overview of attention for article published in BMC Genomics, February 2005
Altmetric Badge

Mentioned by

wikipedia
2 Wikipedia pages

Citations

dimensions_citation
44 Dimensions

Readers on

mendeley
43 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain
Published in
BMC Genomics, February 2005
DOI 10.1186/1471-2164-6-15
Pubmed ID
Authors

Agnes GSH van Rossum, Ellen Schuuring-Scholtes, Vera van Buuren-van Seggelen, Philip M Kluin, Ed Schuuring

Abstract

In human carcinomas, overexpression of cortactin correlates with poor prognosis. Cortactin is an F-actin-binding protein involved in cytoskeletal rearrangements and cell migration by promoting actin-related protein (Arp)2/3 mediated actin polymerization. It shares a high amino acid sequence and structural similarity to hematopoietic lineage cell-specific protein 1 (HS1) although their functions differ considerable. In this manuscript we describe the genomic organization of these two genes in a variety of species by a combination of cloning and database searches. Based on our analysis, we predict the genesis of the actin-binding repeat domain during evolution.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 35%
Student > Master 9 21%
Researcher 5 12%
Student > Bachelor 4 9%
Student > Doctoral Student 3 7%
Other 5 12%
Unknown 2 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 42%
Biochemistry, Genetics and Molecular Biology 9 21%
Medicine and Dentistry 5 12%
Immunology and Microbiology 3 7%
Social Sciences 1 2%
Other 3 7%
Unknown 4 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from BMC Genomics
#3,597
of 10,647 outputs
Outputs of similar age
#36,730
of 141,570 outputs
Outputs of similar age from BMC Genomics
#4
of 17 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,647 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,570 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.