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hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands

Overview of attention for article published in Molecular Cancer, June 2007
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

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2 Wikipedia pages

Citations

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97 Dimensions

Readers on

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49 Mendeley
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Title
hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands
Published in
Molecular Cancer, June 2007
DOI 10.1186/1476-4598-6-37
Pubmed ID
Authors

Mohamed M Desouki, Joseph Geradts, Beatrice Milon, Renty B Franklin, Leslie C Costello

Abstract

The normal human prostate glandular epithelium has the unique function of accumulating high levels of zinc. In prostate cancer this capability is lost as an early event in the development of the malignant cells. The mechanism and factors responsible for the ability of the normal epithelial cells to accumulate zinc and the loss of this capability in the malignant cells need to be identified. We previously reported that Zip1 is an important zinc uptake transporter in prostate cells and is down regulated in the malignant cells in situ along with the depletion of zinc levels. In this report we investigated the expression of two other Zip family zinc transporters, Zip2 and Zip3 in malignant versus nonmalignant (normal and BPH) glands. Zip2 and Zip3 relative protein levels were determined by immunohistochemistry analysis of human prostate tissue sections.

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Thailand 1 2%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 22%
Researcher 8 16%
Student > Bachelor 7 14%
Student > Master 6 12%
Other 3 6%
Other 5 10%
Unknown 9 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 22%
Medicine and Dentistry 8 16%
Biochemistry, Genetics and Molecular Biology 7 14%
Chemistry 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 4 8%
Unknown 13 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2008.
All research outputs
#3,622,884
of 12,483,518 outputs
Outputs from Molecular Cancer
#220
of 1,055 outputs
Outputs of similar age
#79,109
of 271,428 outputs
Outputs of similar age from Molecular Cancer
#7
of 38 outputs
Altmetric has tracked 12,483,518 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,055 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,428 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.