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New strategies and emerging technologies for massively parallel sequencing: applications in medical research

Overview of attention for article published in Genome Medicine, April 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

patent
9 patents
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
69 Dimensions

Readers on

mendeley
128 Mendeley
citeulike
2 CiteULike
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Title
New strategies and emerging technologies for massively parallel sequencing: applications in medical research
Published in
Genome Medicine, April 2009
DOI 10.1186/gm40
Pubmed ID
Authors

Elaine R Mardis

Abstract

A variety of techniques that specifically target human gene sequences for differential capture from a genomic sample, coupled with next-generation, massively parallel DNA sequencing instruments, is rapidly supplanting the combination of polymerase chain reaction and capillary sequencing to discover coding variants in medically relevant samples. These studies are most appropriate for the sample numbers necessary to identify both common and rare single nucleotide variants, as well as small insertion or deletion events, which may cause complex inherited diseases. The same massively parallel sequencers are simultaneously being used for whole-genome resequencing and comprehensive, genome-wide variant discovery in studies of somatic diseases such as cancer. Viral and microbial researchers are using next-generation sequences to identify unknown etiologic agents in human diseases, to study the viral and microbial species that occupy surfaces of the human body, and to inform the clinical management of chronic infectious diseases such as human immunodeficiency virus (HIV). Taken together, these approaches are dramatically accelerating the pace of human disease research and are already impacting patient care.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 4%
United States 4 3%
India 1 <1%
France 1 <1%
Unknown 117 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 33 26%
Student > Ph. D. Student 18 14%
Student > Master 16 13%
Professor 9 7%
Student > Doctoral Student 8 6%
Other 32 25%
Unknown 12 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 57 45%
Biochemistry, Genetics and Molecular Biology 19 15%
Medicine and Dentistry 18 14%
Computer Science 5 4%
Immunology and Microbiology 2 2%
Other 12 9%
Unknown 15 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2021.
All research outputs
#5,611,796
of 26,017,215 outputs
Outputs from Genome Medicine
#1,047
of 1,611 outputs
Outputs of similar age
#21,558
of 110,214 outputs
Outputs of similar age from Genome Medicine
#2
of 13 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,611 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,214 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.