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Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II

Overview of attention for article published in BMC Molecular and Cell Biology, December 2004
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Title
Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II
Published in
BMC Molecular and Cell Biology, December 2004
DOI 10.1186/1472-6807-4-10
Pubmed ID
Authors

Amy K Wernimont, Winfried Weissenhorn

Abstract

Down-regulation of plasma membrane receptors via the endocytic pathway involves their monoubiquitylation, transport to endosomal membranes and eventual sorting into multi vesicular bodies (MVB) destined for lysosomal degradation. Successive assemblies of Endosomal Sorting Complexes Required for Transport (ESCRT-I, -II and III) largely mediate sorting of plasma membrane receptors at endosomal membranes, the formation of multivesicular bodies and their release into the endosomal lumen. In addition, the human ESCRT-II has been shown to form a complex with RNA polymerase II elongation factor ELL in order to exert transcriptional control activity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 6%
Japan 1 3%
France 1 3%
Unknown 32 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 25%
Professor > Associate Professor 5 14%
Student > Bachelor 4 11%
Researcher 4 11%
Student > Master 3 8%
Other 6 17%
Unknown 5 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 47%
Biochemistry, Genetics and Molecular Biology 8 22%
Immunology and Microbiology 3 8%
Medicine and Dentistry 1 3%
Neuroscience 1 3%
Other 1 3%
Unknown 5 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#8,534,528
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#334
of 1,233 outputs
Outputs of similar age
#38,896
of 151,728 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#1
of 3 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 151,728 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them