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Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

Overview of attention for article published in Breast Cancer Research, September 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

patent
2 patents
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
84 Dimensions

Readers on

mendeley
67 Mendeley
citeulike
1 CiteULike
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Title
Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours
Published in
Breast Cancer Research, September 2008
DOI 10.1186/bcr2151
Pubmed ID
Authors

Jürgen Veeck, Nuran Bektas, Arndt Hartmann, Glen Kristiansen, Uwe Heindrichs, Ruth Knüchel, Edgar Dahl

Abstract

Expression of the putative Wnt signalling inhibitor Dickkopf-3 (DKK3) is frequently lost in human cancer tissues because of aberrant 5'-cytosine methylation within the DKK3 gene promoter. Since other Wnt signalling inhibitors have been reported to be targets of epigenetic inactivation in human breast cancer, we questioned if DKK3 expression is also epigenetically silenced during breast carcinogenesis and therefore might contribute to oncogenic Wnt signalling commonly found in this disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
India 1 1%
United States 1 1%
Unknown 64 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 19%
Student > Bachelor 11 16%
Student > Ph. D. Student 10 15%
Student > Master 8 12%
Other 4 6%
Other 12 18%
Unknown 9 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 27%
Biochemistry, Genetics and Molecular Biology 15 22%
Medicine and Dentistry 14 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Chemistry 2 3%
Other 5 7%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#3,798,287
of 25,373,627 outputs
Outputs from Breast Cancer Research
#451
of 2,052 outputs
Outputs of similar age
#12,168
of 101,156 outputs
Outputs of similar age from Breast Cancer Research
#3
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 101,156 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.