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Epigenetic silencing of DSC3 is a common event in human breast cancer

Overview of attention for article published in Breast Cancer Research, June 2005
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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4 X users
wikipedia
1 Wikipedia page

Citations

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95 Dimensions

Readers on

mendeley
49 Mendeley
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Title
Epigenetic silencing of DSC3 is a common event in human breast cancer
Published in
Breast Cancer Research, June 2005
DOI 10.1186/bcr1273
Pubmed ID
Authors

Marc M Oshiro, Christina J Kim, Ryan J Wozniak, Damian J Junk, José L Muñoz-Rodríguez, Jeanne A Burr, Matthew Fitzgerald, Sangita C Pawar, Anne E Cress, Frederick E Domann, Bernard W Futscher

Abstract

Desmocollin 3 (DSC3) is a member of the cadherin superfamily of calcium-dependent cell adhesion molecules and a principle component of desmosomes. Desmosomal proteins such as DSC3 are integral to the maintenance of tissue architecture and the loss of these components leads to a lack of adhesion and a gain of cellular mobility. DSC3 expression is down-regulated in breast cancer cell lines and primary breast tumors; however, the loss of DSC3 is not due to gene deletion or gross rearrangement of the gene. In this study, we examined the prevalence of epigenetic silencing of DSC3 gene expression in primary breast tumor specimens.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 14%
Student > Bachelor 6 12%
Researcher 6 12%
Student > Master 5 10%
Professor 4 8%
Other 7 14%
Unknown 14 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 41%
Biochemistry, Genetics and Molecular Biology 9 18%
Medicine and Dentistry 2 4%
Immunology and Microbiology 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 0 0%
Unknown 15 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2019.
All research outputs
#6,443,957
of 25,374,917 outputs
Outputs from Breast Cancer Research
#736
of 2,053 outputs
Outputs of similar age
#17,177
of 58,256 outputs
Outputs of similar age from Breast Cancer Research
#6
of 20 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,256 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.