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Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer

Overview of attention for article published in BMC Cancer, February 2008
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81 Mendeley
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Title
Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer
Published in
BMC Cancer, February 2008
DOI 10.1186/1471-2407-8-42
Pubmed ID
Authors

Nuran Bektas, Anette ten Haaf, Jürgen Veeck, Peter Johannes Wild, Juliane Lüscher-Firzlaff, Arndt Hartmann, Ruth Knüchel, Edgar Dahl

Abstract

FOXM1 regulates expression of cell cycle related genes that are essential for progression into DNA replication and mitosis. Consistent with its role in proliferation, elevated expression of FOXM1 has been reported in a variety of human tumour entities. FOXM1 is a gene of interest because recently chemical inhibitors of FOXM1 were described to limit proliferation and induce apoptosis in cancer cells in vitro, indicating that FOXM1 inhibitors could represent useful anticancer therapeutics.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Italy 1 1%
Unknown 78 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 27%
Researcher 17 21%
Student > Master 7 9%
Student > Bachelor 7 9%
Professor > Associate Professor 4 5%
Other 11 14%
Unknown 13 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 30%
Biochemistry, Genetics and Molecular Biology 18 22%
Medicine and Dentistry 16 20%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Business, Management and Accounting 1 1%
Other 4 5%
Unknown 14 17%