You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis
|
|---|---|
| Published in |
BMC Microbiology, September 2013
|
| DOI | 10.1186/1471-2180-13-200 |
| Pubmed ID | |
| Authors |
Marina Andrea Forrellad, María Verónica Bianco, Federico Carlos Blanco, Javier Nuñez, Laura Inés Klepp, Cristina Lourdes Vazquez, María de la Paz Santangelo, Rosana Valeria Rocha, Marcelo Soria, Paul Golby, Maximiliano Gabriel Gutierrez, Fabiana Bigi |
| Abstract |
Tuberculosis is one of the leading causes of mortality throughout the world. Mycobacterium tuberculosis, the agent of human tuberculosis, has developed strategies involving proteins and other compounds called virulence factors to subvert human host defences and damage and invade the human host. Among these virulence-related proteins are the Mce proteins, which are encoded in the mce1, mce2, mce3 and mce4 operons of M. tuberculosis. The expression of the mce2 operon is negatively regulated by the Mce2R transcriptional repressor. Here we evaluated the role of Mce2R during the infection of M. tuberculosis in mice and macrophages and defined the genes whose expression is in vitro regulated by this transcriptional repressor. |
Mendeley readers
The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 2% |
| Unknown | 41 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 26% |
| Student > Ph. D. Student | 8 | 19% |
| Student > Doctoral Student | 3 | 7% |
| Lecturer | 2 | 5% |
| Student > Postgraduate | 2 | 5% |
| Other | 7 | 17% |
| Unknown | 9 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 31% |
| Biochemistry, Genetics and Molecular Biology | 6 | 14% |
| Immunology and Microbiology | 5 | 12% |
| Medicine and Dentistry | 4 | 10% |
| Nursing and Health Professions | 1 | 2% |
| Other | 2 | 5% |
| Unknown | 11 | 26% |