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Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

Overview of attention for article published in BMC Cancer, August 2004
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Title
Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors
Published in
BMC Cancer, August 2004
DOI 10.1186/1471-2407-4-43
Pubmed ID
Authors

Catherine L Olsen, Pin-Pin Hsu, Jens Glienke, Gabor M Rubanyi, Alan R Brooks

Abstract

The Hedgehog (Hh) signaling pathway regulates a variety of developmental processes, including vasculogenesis, and can also induce the expression of pro-angiogenic factors in fibroblasts postnatally. Misregulation of the Hh pathway has been implicated in a variety of different types of cancer, including pancreatic and small-cell lung cancer. Recently a putative antagonist of the pathway, Hedgehog-interacting protein (HIP), was identified as a Hh binding protein that is also a target of Hh signaling. We sought to clarify possible roles for HIP in angiogenesis and cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Czechia 1 2%
India 1 2%
Spain 1 2%
Canada 1 2%
Unknown 59 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 20%
Researcher 10 15%
Student > Bachelor 8 12%
Student > Master 8 12%
Professor 5 8%
Other 13 20%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 28%
Biochemistry, Genetics and Molecular Biology 15 23%
Medicine and Dentistry 12 18%
Neuroscience 4 6%
Chemistry 3 5%
Other 3 5%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from BMC Cancer
#2,059
of 8,294 outputs
Outputs of similar age
#18,771
of 53,850 outputs
Outputs of similar age from BMC Cancer
#4
of 17 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,294 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 53,850 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.