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Mendeley readers
Attention Score in Context
| Title |
α-Secretase ADAM10 as Well as αAPPs Is Reduced in Platelets and CSF of Alzheimer Disease Patients
|
|---|---|
| Published in |
Molecular Medicine, February 2002
|
| DOI | 10.1007/bf03402076 |
| Pubmed ID | |
| Authors |
Francesca Colciaghi, Barbara Borroni, Lucia Pastorino, Elena Marcello, Martina Zimmermann, Flaminio Cattabeni, Alessandro Padovani, Monica Di Luca |
| Abstract |
Members of membrane-bound disintegrin metalloproteinases (ADAMs) were shown to be capable of cleaving amyloid precursor protein (APP) at the alpha-cleavage site in different cell systems. One of the candidate alpha-secretases identified in this family is ADAM10. The present study addresses the following major questions: 1) Are the levels of an alpha-secretase candidate (i.e., ADAM10) reduced in accessible cells of Alzheimer Disease (AD) patients? 2) Are ADAM10 levels in the peripheral cells of AD patients related to a concomitant decrease in alpha APPs? |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 105 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 20% |
| Student > Master | 18 | 17% |
| Student > Bachelor | 14 | 13% |
| Researcher | 13 | 12% |
| Student > Doctoral Student | 5 | 5% |
| Other | 17 | 16% |
| Unknown | 19 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 23% |
| Biochemistry, Genetics and Molecular Biology | 21 | 20% |
| Neuroscience | 20 | 19% |
| Medicine and Dentistry | 9 | 8% |
| Chemistry | 5 | 5% |
| Other | 5 | 5% |
| Unknown | 22 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2023.
All research outputs
#8,537,346
of 25,377,790 outputs
Outputs from Molecular Medicine
#419
of 1,206 outputs
Outputs of similar age
#17,144
of 49,280 outputs
Outputs of similar age from Molecular Medicine
#5
of 16 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,206 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 49,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.