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Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study

Overview of attention for article published in BMC Neurology, January 2006
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

wikipedia
2 Wikipedia pages

Readers on

mendeley
53 Mendeley
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Title
Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study
Published in
BMC Neurology, January 2006
DOI 10.1186/1471-2377-6-1
Pubmed ID
Authors

Pascal F Durrenberger, Paul Facer, Maria A Casula, Yiangos Yiangou, Roy A Gray, Iain P Chessell, Nicola C Day, Sue D Collins, Sharon Bingham, Alex W Wilson, David Elliot, Rolfe Birch, Praveen Anand

Abstract

Recent studies show that inflammatory processes may contribute to neuropathic pain. Cyclooxygenase-2 (Cox-2) is an inducible enzyme responsible for production of prostanoids, which may sensitise sensory neurones via the EP1 receptor. We have recently reported that while macrophages infiltrate injured nerves within days of injury, they express increased Cox-2-immunoreactivity (Cox-2-IR) from 2 to 3 weeks after injury. We have now investigated the time course of EP1 and Cox-2 changes in injured human nerves and dorsal root ganglia (DRG), and the chronic constriction nerve injury (CCI) model in the rat.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Researcher 9 17%
Student > Master 6 11%
Professor 6 11%
Student > Bachelor 5 9%
Other 13 25%
Unknown 4 8%
Readers by discipline Count As %
Medicine and Dentistry 26 49%
Agricultural and Biological Sciences 10 19%
Neuroscience 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Psychology 2 4%
Other 5 9%
Unknown 4 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2012.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from BMC Neurology
#845
of 2,432 outputs
Outputs of similar age
#40,100
of 154,450 outputs
Outputs of similar age from BMC Neurology
#2
of 8 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,432 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 154,450 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.