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The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

Overview of attention for article published in Retrovirology, September 2009
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Mentioned by

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3 Wikipedia pages

Citations

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137 Dimensions

Readers on

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58 Mendeley
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Title
The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu
Published in
Retrovirology, September 2009
DOI 10.1186/1742-4690-6-80
Pubmed ID
Authors

Amy J Andrew, Eri Miyagi, Sandra Kao, Klaus Strebel

Abstract

The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4. Recent work identified BST-2/CD317 as a host factor that inhibits HIV-1 virus release in a Vpu sensitive manner. A current working model proposes that BST-2 inhibits virus release by tethering viral particles to the cell surface thereby triggering their subsequent endocytosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 3%
United States 1 2%
United Kingdom 1 2%
Unknown 54 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Researcher 11 19%
Student > Master 6 10%
Student > Bachelor 6 10%
Other 4 7%
Other 12 21%
Unknown 7 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 43%
Biochemistry, Genetics and Molecular Biology 13 22%
Immunology and Microbiology 4 7%
Chemistry 3 5%
Unspecified 1 2%
Other 3 5%
Unknown 9 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from Retrovirology
#408
of 1,106 outputs
Outputs of similar age
#32,526
of 91,720 outputs
Outputs of similar age from Retrovirology
#14
of 33 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 91,720 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.