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RT @MarkQuarter: "Importantly, CD4+ T-cells from patients with Aicardi-Goutières Syndrome harboring mutation in the SAMHD1 gene display an…
RT @MarkQuarter: "Importantly, CD4+ T-cells from patients with Aicardi-Goutières Syndrome harboring mutation in the SAMHD1 gene display an…
"Importantly, CD4+ T-cells from patients with Aicardi-Goutières Syndrome harboring mutation in the SAMHD1 gene display an increased susceptibility to HIV-1 infection that is not further enhanced by VLP-Vpx-treatment." VLP = virus like particles https://t
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells [2012. @IGH_MTP] https://t.co/gQ49f75fgS