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Nav 1.8-Null Mice Show Stimulus-Dependent Deficits in Spinal Neuronal Activity

Overview of attention for article published in Molecular Pain, February 2006
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1 Wikipedia page

Citations

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45 Mendeley
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Title
Nav 1.8-Null Mice Show Stimulus-Dependent Deficits in Spinal Neuronal Activity
Published in
Molecular Pain, February 2006
DOI 10.1186/1744-8069-2-5
Pubmed ID
Authors

Elizabeth A Matthews, John N Wood, Anthony H Dickenson

Abstract

The voltage gated sodium channel Na(v) 1.8 has a highly restricted expression pattern to predominantly nociceptive peripheral sensory neurones. Behaviourally Na(v) 1.8-null mice show an increased acute pain threshold to noxious mechanical pressure and also deficits in inflammatory and visceral, but not neuropathic pain. Here we have made in vivo electrophysiology recordings of dorsal horn neurones in intact anaesthetised Na(v) 1.8-null mice, in response to a wide range of stimuli to further the understanding of the functional roles of Na(v) 1.8 in pain transmission from the periphery to the spinal cord.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Sweden 1 2%
United Kingdom 1 2%
Iran, Islamic Republic of 1 2%
United States 1 2%
Unknown 40 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 33%
Student > Ph. D. Student 6 13%
Student > Bachelor 4 9%
Student > Postgraduate 3 7%
Student > Master 3 7%
Other 7 16%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 38%
Pharmacology, Toxicology and Pharmaceutical Science 7 16%
Neuroscience 4 9%
Medicine and Dentistry 2 4%
Environmental Science 1 2%
Other 4 9%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 March 2014.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from Molecular Pain
#190
of 669 outputs
Outputs of similar age
#45,855
of 175,716 outputs
Outputs of similar age from Molecular Pain
#2
of 5 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,716 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.