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Impact of ε and θ subunits on pharmacological properties of α3β1 GABAA receptors expressed in Xenopus oocytes

Overview of attention for article published in BMC Pharmacology, January 2006
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Title
Impact of ε and θ subunits on pharmacological properties of α3β1 GABAA receptors expressed in Xenopus oocytes
Published in
BMC Pharmacology, January 2006
DOI 10.1186/1471-2210-6-1
Pubmed ID
Authors

Martin Ranna, Saku T Sinkkonen, Tommi Möykkynen, Mikko Uusi-Oukari, Esa R Korpi

Abstract

Gamma-aminobutyric acid type A (GABAA) receptors provide the main inhibitory control in the brain. Their heterogeneity may make it possible to precisely target drug effects to selected neuronal populations. In situ hybridization using rat brain sections has revealed a unique expression of GABAA receptor epsilon and theta subunit transcripts in the locus coeruleus, where they are accompanied at least by alpha3, alpha2, beta1 and beta3 subunits. Here, we studied the pharmacology of the human alpha3beta1, alpha3beta1epsilon, alpha3beta1theta and alpha3beta1epsilontheta receptor subtypes expressed in Xenopus oocytes and compared them with the gamma2 subunit-containing receptors.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Germany 1 3%
Austria 1 3%
Australia 1 3%
Unknown 32 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 33%
Researcher 11 31%
Student > Bachelor 3 8%
Other 2 6%
Student > Master 1 3%
Other 2 6%
Unknown 5 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 36%
Neuroscience 10 28%
Biochemistry, Genetics and Molecular Biology 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Medicine and Dentistry 1 3%
Other 1 3%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2008.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from BMC Pharmacology
#26
of 63 outputs
Outputs of similar age
#40,247
of 154,930 outputs
Outputs of similar age from BMC Pharmacology
#2
of 2 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 63 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 154,930 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.