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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

Overview of attention for article published in BMC Pharmacology, June 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)

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1 patent
2 Wikipedia pages


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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells
Published in
BMC Pharmacology, June 2008
DOI 10.1186/1471-2210-8-9
Pubmed ID

Jillian G Baker


The H3 histamine receptor is a Gi-coupled GPCR that has been proven to exist in different agonist-induced states, including that defined by the protean agonist proxyfan. Several GPCRs are now known to exist in different states. For some of these, antagonist affinity measurement remain constant regardless of the state of the receptor, for others e.g. the beta-adrenoceptors, the antagonist affinity measurements vary considerably depending on which agonist-dependent state is being identified. The purpose of this study was to examine the antagonist affinity measurements at the Gi-coupling human H3 receptor, paying particular attention to measurements made in the presence of full agonists, partial agonists and the proxyfan protean agonist-induced state of the receptor.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 22%
Other 4 22%
Researcher 3 17%
Student > Ph. D. Student 3 17%
Professor > Associate Professor 2 11%
Other 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 39%
Pharmacology, Toxicology and Pharmaceutical Science 3 17%
Medicine and Dentistry 3 17%
Biochemistry, Genetics and Molecular Biology 2 11%
Chemical Engineering 1 6%
Other 1 6%
Unknown 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2020.
All research outputs
of 17,355,315 outputs
Outputs from BMC Pharmacology
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Outputs of similar age
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Outputs of similar age from BMC Pharmacology
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Altmetric has tracked 17,355,315 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 57 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,816 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them