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High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer

Overview of attention for article published in Genome Biology, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
9 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
56 Mendeley
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Title
High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer
Published in
Genome Biology, February 2015
DOI 10.1186/s13059-015-0589-1
Pubmed ID
Authors

Iain Beehuat Tan, Simeen Malik, Kalpana Ramnarayanan, John R McPherson, Dan Liang Ho, Yuka Suzuki, Sarah Boonhsui Ng, Su Yan, Kiat Hon Lim, Dennis Koh, Chew Min Hoe, Chung Yip Chan, Rachel Ten, Brian KP Goh, Alexander YF Chung, Joanna Tan, Cheryl Xueli Chan, Su Ting Tay, Lezhava Alexander, Niranjan Nagarajan, Axel M Hillmer, Choon Leong Tang, Clarinda Chua, Bin Tean Teh, Steve Rozen, Patrick Tan

Abstract

Colorectal cancer with metastases limited to the liver (liver-limited mCRC) is a distinct clinical subset characterized by possible cure with surgery. We performed high-depth sequencing of over 750 cancer-associated genes and copy number profiling in matched primary, metastasis and normal tissues to characterize genomic progression in 18 patients with liver-limited mCRC.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
United Kingdom 1 2%
Germany 1 2%
Unknown 52 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 34%
Student > Ph. D. Student 12 21%
Student > Master 6 11%
Student > Bachelor 4 7%
Student > Doctoral Student 3 5%
Other 5 9%
Unknown 7 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 30%
Biochemistry, Genetics and Molecular Biology 15 27%
Medicine and Dentistry 11 20%
Computer Science 2 4%
Environmental Science 1 2%
Other 2 4%
Unknown 8 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2015.
All research outputs
#1,891,911
of 25,373,627 outputs
Outputs from Genome Biology
#1,581
of 4,467 outputs
Outputs of similar age
#26,615
of 367,418 outputs
Outputs of similar age from Genome Biology
#27
of 65 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 367,418 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.