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The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase

Overview of attention for article published in BMC Molecular and Cell Biology, April 2008
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1 Wikipedia page

Citations

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30 Mendeley
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Title
The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase
Published in
BMC Molecular and Cell Biology, April 2008
DOI 10.1186/1471-2091-9-13
Pubmed ID
Authors

Fernanda Ely, José ES Nunes, Evelyn K Schroeder, Jeverson Frazzon, Mário S Palma, Diógenes S Santos, Luiz A Basso

Abstract

The emergence of multi- and extensively-drug resistant Mycobacterium tuberculosis strains has created an urgent need for new agents to treat tuberculosis (TB). The enzymes of shikimate pathway are attractive targets to the development of antitubercular agents because it is essential for M. tuberculosis and is absent from humans. Chorismate synthase (CS) is the seventh enzyme of this route and catalyzes the NADH- and FMN-dependent synthesis of chorismate, a precursor of aromatic amino acids, naphthoquinones, menaquinones, and mycobactins. Although the M. tuberculosis Rv2540c (aroF) sequence has been annotated to encode a chorismate synthase, there has been no report on its correct assignment and functional characterization of its protein product.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Brazil 1 3%
Unknown 28 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 20%
Researcher 4 13%
Student > Bachelor 4 13%
Student > Master 3 10%
Librarian 2 7%
Other 6 20%
Unknown 5 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 27%
Biochemistry, Genetics and Molecular Biology 7 23%
Sports and Recreations 2 7%
Chemistry 2 7%
Immunology and Microbiology 1 3%
Other 3 10%
Unknown 7 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2011.
All research outputs
#8,534,976
of 25,374,647 outputs
Outputs from BMC Molecular and Cell Biology
#334
of 1,233 outputs
Outputs of similar age
#31,616
of 89,375 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#6
of 16 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,375 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.