Title |
Effect of rosuvastatin on outcomes in chronic haemodialysis patients – design and rationale of the AURORA study
|
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Published in |
Current Controlled Trials in Cardiovascular Medicine, May 2005
|
DOI | 10.1186/1468-6708-6-9 |
Pubmed ID | |
Authors |
Bengt Fellström, Faiez Zannad, Roland Schmieder, Hallvard Holdaas, Alan Jardine, Helen Rose, Wim Wilpshaar |
Abstract |
Patients with end-stage renal disease (ESRD) are at high risk of cardiovascular events. Multiple risk factors for atherosclerosis are present in ESRD and may contribute to the increased risk of cardiovascular mortality in this population. In contrast to patients with normal renal function, the benefits of modifying lipid levels on cardiovascular outcomes in patients with ESRD on haemodialysis have yet to be confirmed in large prospective randomised trials. A study to evaluate the Use of Rosuvastatin in subjects On Regular haemodialysis: an Assessment of survival and cardiovascular events (AURORA) will be the first large-scale international trial to assess the effects of statin therapy on cardiovascular morbidity and mortality in ESRD patients on chronic haemodialysis. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 42 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 10% |
Researcher | 4 | 10% |
Student > Postgraduate | 4 | 10% |
Professor | 3 | 7% |
Student > Bachelor | 3 | 7% |
Other | 10 | 24% |
Unknown | 14 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 40% |
Business, Management and Accounting | 2 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Nursing and Health Professions | 1 | 2% |
Other | 4 | 10% |
Unknown | 15 | 36% |