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Mendeley readers
| Title |
Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway
|
|---|---|
| Published in |
Journal of Experimental & Clinical Cancer Research, December 2008
|
| DOI | 10.1186/1756-9966-27-86 |
| Pubmed ID | |
| Authors |
Leticia Oliveira-Ferrer, Jessica Hauschild, Walter Fiedler, Carsten Bokemeyer, Johannes Nippgen, Ilhan Celik, Gunter Schuch |
| Abstract |
The antiangiogenic agent cilengitide disrupts integrin binding to the extracellular matrix leading to apoptosis of activated endothelial cells. Integrins are also widely expressed in malignant glioma and integrin inhibitors may directly target tumor cells in this disease. Aim of the current study was to investigate effects of cilengitide on endothelial and glioma cells on molecular and cellular levels. |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 3% |
| United States | 1 | 1% |
| Italy | 1 | 1% |
| Unknown | 69 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 25% |
| Student > Ph. D. Student | 13 | 18% |
| Student > Master | 10 | 14% |
| Student > Doctoral Student | 6 | 8% |
| Student > Bachelor | 4 | 5% |
| Other | 11 | 15% |
| Unknown | 11 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 34% |
| Medicine and Dentistry | 12 | 16% |
| Biochemistry, Genetics and Molecular Biology | 10 | 14% |
| Neuroscience | 3 | 4% |
| Computer Science | 2 | 3% |
| Other | 9 | 12% |
| Unknown | 12 | 16% |