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MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

Overview of attention for article published in BMC Cancer, July 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

patent
1 patent
wikipedia
1 Wikipedia page

Citations

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334 Dimensions

Readers on

mendeley
121 Mendeley
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Title
MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
Published in
BMC Cancer, July 2010
DOI 10.1186/1471-2407-10-367
Pubmed ID
Authors

Zhang Chun-zhi, Han Lei, Zhang An-ling, Fu Yan-chao, Yue Xiao, Wang Guang-xiu, Jia Zhi-fan, Pu Pei-yu, Zhang Qing-yu, Kang Chun-sheng

Abstract

MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle progression via direct targeting of p27 and p57 in various human malignancies. However, the roles of miR-221 and miR-222 have not been reported in human gastric cancer. In this study, we examined the impact of miR-221 and miR-222 on human gastric cancer cells, and identified target genes for miR-221 and miR-222 that might mediate their biology.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
India 1 <1%
United States 1 <1%
Unknown 118 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 26%
Researcher 19 16%
Student > Master 19 16%
Student > Bachelor 10 8%
Student > Doctoral Student 9 7%
Other 15 12%
Unknown 18 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 31%
Biochemistry, Genetics and Molecular Biology 31 26%
Medicine and Dentistry 19 16%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Engineering 2 2%
Other 5 4%
Unknown 25 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2014.
All research outputs
#4,696,781
of 22,790,780 outputs
Outputs from BMC Cancer
#1,204
of 8,294 outputs
Outputs of similar age
#19,662
of 94,914 outputs
Outputs of similar age from BMC Cancer
#11
of 59 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,294 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,914 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.