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Mendeley readers
Attention Score in Context
| Title |
The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins
|
|---|---|
| Published in |
Microbial Cell Factories, June 2010
|
| DOI | 10.1186/1475-2859-9-49 |
| Pubmed ID | |
| Authors |
Mouna Guerfal, Stefan Ryckaert, Pieter P Jacobs, Paul Ameloot, Kathleen Van Craenenbroeck, Riet Derycke, Nico Callewaert |
| Abstract |
The unfolded protein response (UPR) in eukaryotes upregulates factors that restore ER homeostasis upon protein folding stress and in yeast is activated by a non-conventional splicing of the HAC1 mRNA. The spliced HAC1 mRNA encodes an active transcription factor that binds to UPR-responsive elements in the promoter of UPR target genes. Overexpression of the HAC1 gene of S. cerevisiae can reportedly lead to increased production of heterologous proteins. To further such studies in the biotechnology favored yeast Pichia pastoris, we cloned and characterized the P. pastoris HAC1 gene and the splice event. |
Mendeley readers
The data shown below were compiled from readership statistics for 260 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 6 | 2% |
| Austria | 4 | 2% |
| India | 1 | <1% |
| Chile | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 246 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 67 | 26% |
| Researcher | 45 | 17% |
| Student > Master | 29 | 11% |
| Student > Bachelor | 23 | 9% |
| Student > Doctoral Student | 16 | 6% |
| Other | 32 | 12% |
| Unknown | 48 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 100 | 38% |
| Biochemistry, Genetics and Molecular Biology | 88 | 34% |
| Chemical Engineering | 5 | 2% |
| Engineering | 5 | 2% |
| Environmental Science | 3 | 1% |
| Other | 10 | 4% |
| Unknown | 49 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2023.
All research outputs
#2,286,450
of 25,090,809 outputs
Outputs from Microbial Cell Factories
#64
of 1,793 outputs
Outputs of similar age
#8,011
of 99,819 outputs
Outputs of similar age from Microbial Cell Factories
#2
of 9 outputs
Altmetric has tracked 25,090,809 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,793 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 99,819 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.