Title |
Comparison of dot chromosome sequences from D. melanogaster and D. virilisreveals an enrichment of DNA transposon sequences in heterochromatic domains
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Published in |
Genome Biology, February 2006
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DOI | 10.1186/gb-2006-7-2-r15 |
Pubmed ID | |
Authors |
Elizabeth E Slawson, Christopher D Shaffer, Colin D Malone, Wilson Leung, Elmer Kellmann, Rachel B Shevchek, Carolyn A Craig, Seth M Bloom, James Bogenpohl, James Dee, Emiko TA Morimoto, Jenny Myoung, Andrew S Nett, Fatih Ozsolak, Mindy E Tittiger, Andrea Zeug, Mary-Lou Pardue, Jeremy Buhler, Elaine R Mardis, Sarah CR Elgin |
Abstract |
Chromosome four of Drosophila melanogaster, known as the dot chromosome, is largely heterochromatic, as shown by immunofluorescent staining with antibodies to heterochromatin protein 1 (HP1) and histone H3K9me. In contrast, the absence of HP1 and H3K9me from the dot chromosome in D. virilis suggests that this region is euchromatic. D. virilis diverged from D. melanogaster 40 to 60 million years ago. |
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Geographical breakdown
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Brazil | 3 | 6% |
Canada | 2 | 4% |
Spain | 1 | 2% |
Netherlands | 1 | 2% |
Unknown | 38 | 79% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 35% |
Student > Ph. D. Student | 9 | 19% |
Professor > Associate Professor | 6 | 13% |
Student > Bachelor | 5 | 10% |
Student > Master | 5 | 10% |
Other | 6 | 13% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 1 | 2% |
Other | 1 | 2% |