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Mendeley readers
Attention Score in Context
Title |
APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication
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Published in |
Retrovirology, August 2008
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DOI | 10.1186/1742-4690-5-72 |
Pubmed ID | |
Authors |
Lin Li, Dong Liang, Jing-yun Li, Richard Y Zhao |
Abstract |
Although APOBEC3G protein is a potent and innate anti-HIV-1 cellular factor, HIV-1 Vif counteracts the effect of APOBEC3G by promoting its degradation through proteasome-mediated proteolysis. Thus, any means that could prevent APOBEC3G degradation could potentially enhance its anti-viral effect. The UBA2 domain has been identified as an intrinsic stabilization signal that protects protein from proteasomal degradation. In this pilot study, we tested whether APOBEC3G, when it is fused with UBA2, can resist Vif-mediated proteasomal degradation and further inhibit HIV-1 infection. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 4% |
Unknown | 27 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 25% |
Professor | 4 | 14% |
Student > Ph. D. Student | 3 | 11% |
Student > Master | 3 | 11% |
Student > Bachelor | 2 | 7% |
Other | 5 | 18% |
Unknown | 4 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 39% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Immunology and Microbiology | 2 | 7% |
Psychology | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Other | 4 | 14% |
Unknown | 4 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 December 2022.
All research outputs
#4,862,572
of 23,415,749 outputs
Outputs from Retrovirology
#236
of 1,116 outputs
Outputs of similar age
#16,443
of 83,435 outputs
Outputs of similar age from Retrovirology
#2
of 6 outputs
Altmetric has tracked 23,415,749 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,116 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 83,435 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.